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Series on BIOMECHANICS   ISSN 1313-2458
Array ( [session_started] => 1753993929 [LANGUAGE] => EN [LEPTON_SESSION] => 1 )
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Current trends in transcatheter aortic valve implantation modelling and simulation
N. Pilorcid, G. Selivanov, M. Seleznev, T. Pandelaniorcid, O.Krestyaninovorcid, F. Nemavholaorcid, A. G. Kuchumovorcid
Abstract: Transcatheter aortic implantation (TAVI) is an important minimally invasive procedure used to treat aortic stenosis, especially in high-risk patients. In recent years, there has been a significant increase in the number of TAVI procedures due to improved clinical outcomes and expanded indications for this technology in low- and intermediate-risk groups. Objective: This article provides an overview of current technologies and methods used to model and optimize transcatheter aortic valves. Materials and Methods: The most prominent and authoritative scientific databases were utilized, including PubMed, Scopus, Web of Science, and Google Scholar papers published between 2010 and 2025.Search queries included combinations of keywords such as «TAVI», «transcatheter aortic valve implantation», «aortic stenosis», «computational modeling of TAVI», «fluid-structure interaction» and «hemodynamics of TAVI». Results: We performed a systematic literature survey of peer-reviewed studies on numerical simulation of TAVI devices, focusing on Bernoulli–Euler beam approximations and Auricchio-Taylor model for shape memory stent, isotropic and anisotropic hyperelastic models of leaflet and skirt tissues–including Mooney–Rivlin, Ogden, and modified Holzapfel–Gasser–Ogden formulations and coupling strategies in fluid–structure interaction (FSI) frameworks. Key material parameters, modeling assumptions, and solver methodologies were extracted and compared. Discussion: This review provides a comprehensive analysis of the status and trends in TAVI, with an emphasis on the use of computer models and experimental studies to improve clinical outcomes. In addition, the future direction in personalized modeling using digital patient twins is discussed, allowing for accurate prediction of procedure outcomes and improved patient-specific valve selection.

Series on Biomechanics, Vol.39, No.2 (2025), 3-23
DOI: 10.7546/SB.01.02.2025


Keywords: Aortic valve; fluid-structure interaction; transcatheter aortic valve implantation
References: (click to open/close)
DOI: 10.7546/SB.01.02.2025
Date published: 2025-07-09
(Price of one pdf file: 39.00 BGN/20.00 EUR)