Hemorheological disturbances in patients with chronic form of atrial fibrillation

M.Gotsadze, T.Kandashvili, N.Narsia, N.Momtselidze, M.Mantskava, N.Antonova

Abstract: According to the World Health Organization (WHO), atrial fibrillation affects 1% of the World's population. Ischemic strokes and systemic thromboembolism are common complications of this rhythm disorder. Although the disease has been studied in various ways, hemorheological characteristics and their potential relationship with the progression of arrhythmias remain unclear. There are no physiological or pathophysiological processes at the microcirculation level, where hemorheology is important in terms of intensity and volume flow rate. When developing the research design, we accounted for these issues. The aim of the study was to identify the rheological characteristics in patients with chronic forms of atrial fibrillation, as well as to clarify the aspects of the interdependence between the severity of the disease and the rheological parameters.Thirty six patients with chronic forms of atrial fibrillation were examined. From the final processing of the material, the following results were obtained: the difference between patients with atrial fibrillation and the control group was reliable, with a confidence index of 1%. The results show that regardless of their course, all rheological characteristics in patients with atrial fibrillation are impaired.

Series on Biomechanics, Vol.37, No.2 (2023), 95-102
DOI: 10.7546/SB.10.02.2023

Keywords: atrial fibrillation; blood flow; erythrocyte aggregation; Hemorheology

Date published: 2023-06-19