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Series on BIOMECHANICS   ISSN 1313-2458
Array ( [session_started] => 1718957380 [LANGUAGE] => EN [LEPTON_SESSION] => 1 )
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Complex dynamics of a colorectal cancer model
S. Nikolov
Abstract: Mathematical models of the stem cell and semi-differentiated cell populations in colonic crypts can contribute to a better understanding of basic mechanisms underlying tissue organization. We here study the complex dynamic behaviour of a time delay model that describes stem cells and semi-differentiated cells in the niche of colonic crypts. We analyze the conditions for the various regimes that would lead to oscillations. The work presented here the first description of a chaotic system describing stem cell and semi-differentiated cell population dynamics in colonic crypts.
Keywords: bifurcation analysis; Colorectal cancer; complex behavior; time delay model
Date published: 2015-06-09
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