Съвременни тенденции в моделирането на транскатетърна имплантация на аортна клапа
Никита Пил
, Глеб Селиванов, Максим Селезнев, Таняни Панделани
, Олег Крестьянинов
, Фулуфело Немавхола
, Алексей Кучумов
Резюме: Транскатетърната имплантация на аортна клапа (TAVI) е важна минимално инвазивна процедура, използвана за лечение на аортна стеноза, особено при пациенти с висок риск. През последните години се наблюдава значително увеличение на броя на TAVI процедурите поради подобрените клинични резултати и разширените показания за тази технология при групи с нисък и среден риск. Цел: Тази статия предоставя преглед на съвременните технологии и методи, използвани за моделиране и оптимизиране на транскатетърни аортни клапи. Материали и методи: Използвани са най-известните и авторитетни научни бази данни, включително PubMed, Scopus, Web of Science и Google Scholar, публикувани между 2010 и 2025 г. Търсените заявки включваха комбинации от ключови думи като „TAVI“, „транскатетърна имплантация на аортна клапа“, „аортна стеноза“, „изчислително моделиране на TAVI“, „взаимодействие флуид-структура“ и „хемодинамика на TAVI“. Резултати: Проведохме систематичен преглед на литературата на рецензирани изследвания върху численото моделиране на TAVI устройства, като се фокусирахме върху теорията на лъча на Бернули-Ойлер и модела на Аурикио-Тейлър за стент с памет на формата, изотропни и анизотропни хипереластични модели на тъкани на платната и полата, включително модела на Муни-Ривлин, Огдън и модифицирания модел на Холцапфел-Гасер-Огдън, и стратегии за свързване в системи за взаимодействие флуид-твърдо тяло. Бяха идентифицирани и сравнени ключови параметри на материалите, допускания за моделиране и методологии за решаване на проблеми. Дискусия: Този преглед представя цялостен анализ на състоянието и тенденциите в TAVR, като се набляга на използването на изчислителни модели и експериментални изследвания за подобряване на клиничните резултати. Освен това се обсъжда бъдещата посока на персонализираното моделиране с помощта на цифрови близнаци на пациента, което позволява точно прогнозиране на процедурните резултати и подобрен избор на клапа, специфичен за пациента. <br>
Ключови думи: аортна клапа; взаимодействие флуид-твърдо тяло; транскатетърна имплантация на аортна клапа
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| Дата на публикуване: 2025-07-09
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